Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953278 | 0.79 | KMT2A (0.36) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL4948741 | 0.79 | KMT2A (0.41) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL8332629 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL3994109 | 0.76 | KIF11 (0.46) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1590227 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL8072121 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL7133636 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL2490410 | 0.70 | SLC6A11 (0.50) | KMT2AMEN1SLC6A1 | |
| SCHEMBL992028 | 0.70 | SLC6A11 (0.50) | KMT2AMEN1SLC6A1 | |
| SCHEMBL4627811 | 0.69 | ALDH1A1 (0.42) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107489-A1 | APTAMER-BASED REAGENTS FOR A TARGET MOLECULE INVOLVED IN HEMOSTASIS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2008-09-12 | — | — | WO | disclosed |