Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 10/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951215 | 0.85 | PTGS2 (0.42) | ALDH1A1PTGS2MEN1NPC1MAPT | |
| SCHEMBL4949007 | 0.84 | GRM5 (0.36) | — | |
| SCHEMBL4950102 | 0.83 | PTGS1 (0.41) | ALDH1A1PTGS2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4950754 | 0.83 | SCN5A (0.37) | ALDH1A1PTGS2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4952527 | 0.82 | PTGS2 (0.36) | PTGS2 | |
| SCHEMBL5141284 | 0.81 | SCN9A (0.47) | — | |
| SCHEMBL4950448 | 0.81 | ALDH1A1 (0.40) | ALDH1A1PLA2G7MEN1MAPTKMT2A | |
| SCHEMBL4950128 | 0.80 | GRIA2 (0.52) | MEN1KMT2AGRIA2KDM1A | |
| SCHEMBL4952472 | 0.78 | F11 (0.35) | PTGS2 | |
| SCHEMBL4950017 | 0.77 | EIF4E (0.39) | PTGS2SMN1; SMN2GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |