Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30414006 | 1.00 | CYP3A4 (0.68) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL3064552 | 0.86 | CYP3A4 (0.68) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL25351591 | 0.86 | CYP3A4 (0.75) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL20959 | 0.81 | CYP3A4 (1.00) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL30839096 | 0.81 | CYP3A4 (0.74) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL746125 | 0.81 | CYP3A4 (0.74) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL29510426 | 0.81 | CYP3A4 (1.00) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| Methane SCHEMBL4169772 | 0.79 | CYP3A4 (0.95) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL3334778 | 0.77 | CYP3A4 (0.68) | CYP3A4NPC1MAPTMAPK1RAB9A | |
| SCHEMBL16773414 | 0.76 | CYP3A4 (0.65) | CYP3A4NPC1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332718-A | Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | 苏州亚科科技股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-119923385-A | Inhibitors of RNA helicase DHX9 and uses thereof | 埃克森特治疗公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-117088746-A | Preparation method of parylene series products and parylene series products | 苏州亚科科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116332718-A | Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | 苏州亚科科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332718-A | Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | 苏州亚科科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332718-A | Preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | 苏州亚科科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-103539632-B | Method for preparing octafluoro [2,2] dimeric p-xylene by catalysis | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103102242-B | Simple high-efficiency preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103102242-B | Simple high-efficiency preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103102242-B | Simple high-efficiency preparation method of 1, 4-bis (chlorodifluoromethyl) benzene | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (CN) | 2015-09-02 | — | — | CN | disclosed |
| EP-1910322-B1 | NOVEL DEUTERATED BENZO [D][1,3]-DIOXOL DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | CONCERT PHARMACEUTICALS INC (US) | 2012-09-05 | — | — | EP | disclosed |
| CN-102557864-A | Method for preparing 1, 4-bis (chlorodifluoromethyl) benzene | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-11 | — | — | CN | disclosed |
| CN-102557864-A | Method for preparing 1, 4-bis (chlorodifluoromethyl) benzene | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-11 | — | — | CN | disclosed |
| US-20110130424-A1 | SUBSTITUTED PHENYLPIPERIDINES WITH SEROTONINERGIC ACTIVITY AND ENHANCED THERAPEUTIC PROPERTIES | AUSPEX PHARMACEUTICALS, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20090143432-A1 | Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| US-20080287495-A1 | Novel benzo[d][1,3]-dioxol derivatives | CONCERT PHARMACEUTICALS INC. | 2008-11-20 | — | — | US | disclosed |
| WO-2008045987-A1 | NOVEL METHODS FOR PRODUCING THERMOPLASTIC FLUOROPOLYMERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-04-17 | — | — | WO | disclosed |
| EP-1910322-A2 | NOVEL BENZO [D][1,3]-DIOXOL DERIVATIVES | Concert Pharmaceuticals Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070112031-A1 | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties | AUSPEX PHARMACEUTICALS, INC. | 2007-05-17 | — | — | US | disclosed |
| WO-2007016431-A2 | NOVEL BENZO [D] [1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287495-A1 | Novel benzo[d][1,3]-dioxol derivatives | TPH1, HTR1D, HTR1A | CYP3A4 269/4885NPC1 929/4885MAPT 1006/4885 |
| US-20090143432-A1 | Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof | COMT, DRD2, DRD3 | CYP3A4 160/4885NPC1 3262/4885MAPT 3518/4885 |
| US-20070112031-A1 | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties | SLC6A4, HTR4, HTR5A | CYP3A4 255/4885NPC1 1089/4885MAPT 433/4885 |
| US-20110130424-A1 | SUBSTITUTED PHENYLPIPERIDINES WITH SEROTONINERGIC ACTIVITY AND ENHANCED THERAPEUTIC PROPERTIES | SLC6A4, HTR4, HTR5A | CYP3A4 255/4885NPC1 1089/4885MAPT 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.