SCHEMBL4953282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4952253	0.93	OPRM1 (0.45)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4953313	0.93	HTR1A (0.49)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4953406	0.85	HTR1A (0.46)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4952842	0.85	FKBP1A (0.56)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4952515	0.85	MEN1 (0.59)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4948817	0.84	MEN1 (0.50)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4955471	0.84	FKBP1A (0.47)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4954092	0.83	ATF4 (0.56)	HTR1AHTR2AHTR7HTR6TDP1
	SCHEMBL4948705	0.83	OPRM1 (0.45)	HTR1AHTR2AHTR7HTR6MEN1
	SCHEMBL4951614	0.82	OPRM1 (0.44)	HTR1AHTR2AHTR7HTR6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.