Water

Water

SCHEMBL4957698

O.O.O.O.O.[Cl-].[Cl-].[Ni+2]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2295403 1.00 KDM3A (0.33)
Water SCHEMBL225664 1.00
Water SCHEMBL9317506 1.00 KDM3A (0.33)
Water SCHEMBL7546680 1.00
Water SCHEMBL6343678 1.00
Water SCHEMBL6308023 1.00
Water SCHEMBL117189 1.00
Water SCHEMBL2708008 1.00 KDM3A (0.33)
Water SCHEMBL1552649 1.00
Water SCHEMBL28312514 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118988244-B Bismuth-based bimetallic aerogel adsorbent and preparation method and application thereof 西南科技大学 2025-04-29 CN claimed
CN-118988244-A Bismuth-based bimetallic aerogel adsorbent and preparation method and application thereof 西南科技大学 2024-11-22 CN claimed
CN-107572604-B Preparation method of nickel tungstate nanorod supercapacitor material 南阳理工学院 2021-04-02 CN claimed
EP-0393169-B1 METHOD FOR PLATING ON TITANIUM Hughes Aircraft Company (US) 1992-09-16 EP claimed
EP-0393169-A1 METHOD FOR PLATING ON TITANIUM. HUGHES AIRCRAFT CO (US) 1990-10-24 EP claimed
US-4938850-A ELECTROLESS NICKEL COATING HUGHES AIRCRAFT COMPANY (US) 1990-07-03 US claimed
WO-1990003457-A1 METHOD FOR PLATING ON TITANIUM HUGHES AIRCRAFT COMPANY (US) 1990-04-05 WO claimed
CN-118988244-B Bismuth-based bimetallic aerogel adsorbent and preparation method and application thereof 西南科技大学 2025-04-29 CN disclosed
EP-4538382-A1 CAROTENOID PRODUCTION Faculty of Biology & CeBiTec Universität Bielefeld (DE) 2025-04-16 EP disclosed
CN-118988244-A Bismuth-based bimetallic aerogel adsorbent and preparation method and application thereof 西南科技大学 2024-11-22 CN disclosed
CN-107572604-B Preparation method of nickel tungstate nanorod supercapacitor material 南阳理工学院 2021-04-02 CN disclosed
EP-1441047-B1 METHOD FOR FORMING ELECTROPLATED COATING ON SURFACE OF ARTICLE HITACHI METALS LTD (JP) 2016-01-20 EP disclosed
US-7449100-B2 Method for forming electroplating film on surfaces of articles HITACHI METALS, LTD. (JP) 2008-11-11 US disclosed
EP-1441047-A1 METHOD FOR FORMING ELECTROPLATED COATING ON SURFACE OF ARTICLE SUMITOMO SPECIAL METALS CO., LTD. (JP) 2004-07-28 EP disclosed
US-20040069650-A1 Method for forming electroplated coating on surface of article HITACHI METALS, LTD. (JP) 2004-04-15 US disclosed
EP-0393169-B1 METHOD FOR PLATING ON TITANIUM Hughes Aircraft Company (US) 1992-09-16 EP disclosed
EP-0393169-A1 METHOD FOR PLATING ON TITANIUM. HUGHES AIRCRAFT CO (US) 1990-10-24 EP disclosed
US-4938850-A ELECTROLESS NICKEL COATING HUGHES AIRCRAFT COMPANY (US) 1990-07-03 US disclosed
WO-1990003457-A1 METHOD FOR PLATING ON TITANIUM HUGHES AIRCRAFT COMPANY (US) 1990-04-05 WO disclosed