Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4957698 | 1.00 | — | — | |
| Water SCHEMBL2295403 | 1.00 | KDM3A (0.33) | KDM3A | |
| Water SCHEMBL225664 | 1.00 | — | — | |
| Water SCHEMBL9317506 | 1.00 | KDM3A (0.33) | KDM3A | |
| Water SCHEMBL7546680 | 1.00 | — | — | |
| Water SCHEMBL6343678 | 1.00 | — | — | |
| Water SCHEMBL6308023 | 1.00 | — | — | |
| Water SCHEMBL117189 | 1.00 | — | — | |
| Water SCHEMBL1552649 | 1.00 | — | — | |
| Water SCHEMBL28312514 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108376742-B | Preparation method and application of cerium oxide-based solar cell nano powder material | 湖南文理学院 | 2021-12-07 | — | — | CN | claimed |
| CN-116987652-A | Genetically engineered bacterium for producing D-pantothenic acid, construction method and application | 浙江工业大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-108376742-B | Preparation method and application of cerium oxide-based solar cell nano powder material | 湖南文理学院 | 2021-12-07 | — | — | CN | disclosed |
| CN-112538098-B | Alpha-sulfonic acid-beta-diimine nickel complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2021-11-26 | — | — | CN | disclosed |
| CN-110983392-B | Method for electroplating zinc-nickel alloy, magnet, electroplating solution and use of potassium chloride | 包头天和磁材科技股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-11008657-B2 | Composition for catalyst-free electroless plating and method for electroless plating using the same | KOREA INSTITUTE OF MATERIALS SCIENCE (KR) | 2021-05-18 | — | — | US | disclosed |
| CN-112538098-A | Alpha-sulfonic acid-beta-diimine nickel complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-110983392-A | Method for electroplating zinc-nickel alloy, magnet, electroplating solution and use of potassium chloride | 包头天和磁材科技股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| US-20190256981-A1 | COMPOSITION FOR CATALYST-FREE ELECTROLESS PLATING AND METHOD FOR ELECTROLESS PLATING USING THE SAME | KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) | 2019-08-22 | — | — | US | disclosed |
| US-10301278-B2 | 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2 | NOVARTIS AG (CH) | 2019-05-28 | — | — | US | disclosed |
| EP-2048224-B1 | MICROORGANISM WITH REPLACED GENE AND PROCESS FOR PRODUCING POLYESTER USING THE SAME | KANEKA CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-1789042-B1 | 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2012-05-02 | — | — | EP | disclosed |
| US-7579359-B2 | 1-alkoxy 1H-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-08-25 | — | — | US | disclosed |
| EP-1789042-A4 | 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-2048224-A1 | MICROORGANISM WITH REPLACED GENE AND PROCESS FOR PRODUCING POLYESTER USING THE SAME | Kaneka Corporation (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-20090005376-A1 | imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-01 | — | — | US | disclosed |
| US-7384766-B2 | Gene-substituted microorganisms, and production method of polyesters using the same | KANEKA CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20080038801-A1 | Gene-substituted microorganisms, and production method of polyesters using the same | KANEKA CORPORATION | 2008-02-14 | — | — | US | disclosed |
| EP-1789042-A2 | 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006028962-A2 | 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301278-B2 | 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2 | PTPN1, PTPN5, PTPN7 | KDM3A 1063/4885 |
| US-20090005376-A1 | imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases | IL2, IL4, IRF3 | KDM3A 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.