SCHEMBL4959202

SCHEMBL4959202

O=C(OC(=O)c1cccc2c(Br)cccc12)c1cccc2c(Br)cccc12

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.56
KMT2A Q03164 11/20 0.53
MEN1 O00255 8/20 0.53
AHR P35869 1/20 0.49
PARP1 P09874 1/20 0.40
MAPT P10636 2/20 0.39
HPGD P15428 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 2/20 0.38
GAA P10253 2/20 0.38
PKM P14618 1/20 0.38
MIF P14174 1/20 0.37
KDM4E B2RXH2 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30848483 1.00 PRNP (0.56) PRNPKMT2AMEN1AHRPARP1
SCHEMBL17969208 0.91 PRNP (0.53) PRNPKMT2AMEN1AHRHPGD
SCHEMBL1518036 0.88 PRNP (0.47) PRNPKMT2AMEN1AHRMAPT
SCHEMBL28792814 0.85 KMT2A (0.51) PRNPKMT2AMEN1AHRALDH1A1
SCHEMBL29583255 0.85 KMT2A (0.57) PRNPKMT2AMEN1AHRALDH1A1
SCHEMBL2646933 0.85 KMT2A (0.57) PRNPKMT2AMEN1AHRALDH1A1
SCHEMBL16447301 0.81 PRNP (0.38) PRNPKMT2AMEN1AHRMAPT
SCHEMBL29549088 0.80 PRNP (0.49) PRNPKMT2AMEN1AHRPKM
SCHEMBL1936278 0.80 PRNP (0.49) PRNPKMT2AMEN1AHRPKM
SCHEMBL7848859 0.80 TSHR (0.59) PRNPKMT2AMEN1AHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR PRNP 920/4885KMT2A 3653/4885MEN1 2817/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT PRNP 2494/4885KMT2A 3047/4885MEN1 1113/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 PRNP 3720/4885KMT2A 2738/4885MEN1 3449/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 PRNP 4448/4885KMT2A 1465/4885MEN1 3755/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH PRNP 1303/4885KMT2A 1508/4885MEN1 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.