Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748186 | 0.77 | ALDH1A1 (0.48) | ALDH1A1RAB9AGALR3BRD4TSHR | |
| SCHEMBL6365366 | 0.74 | ALDH1A1 (0.50) | ALDH1A1RAB9AGALR3BRD4TSHR | |
| SCHEMBL106062 | 0.73 | TSHR (0.50) | ALDH1A1RAB9AGALR3HTTTSHR | |
| SCHEMBL20893295 | 0.73 | TSHR (0.42) | ALDH1A1RAB9AGALR3TAS2R14TSHR | |
| SCHEMBL4959889 | 0.73 | RAB9A (0.47) | ALDH1A1RAB9AHTTNPC1KDM4E | |
| Acetone SCHEMBL2552960 | 0.72 | TSHR (0.54) | ALDH1A1RAB9AGALR3HTTTSHR | |
| SCHEMBL4618290 | 0.72 | ALDH1A1 (0.56) | ALDH1A1RAB9AGALR3TDP1HTT | |
| SCHEMBL26728285 | 0.72 | P2RX7 (0.51) | ALDH1A1RAB9AGALR3BRD4TSHR | |
| SCHEMBL15955664 | 0.72 | FFAR1 (0.44) | ALDH1A1RAB9AGALR3TAS2R14TDP1 | |
| Ethane SCHEMBL2154770 | 0.71 | TSHR (0.48) | ALDH1A1RAB9AGALR3HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |