Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.40 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.40 |
| ▸ | RPS17 | P08708 | 2/20 | 0.40 |
| ▸ | RPSA | P08865 | 2/20 | 0.40 |
| ▸ | RPS2 | P15880 | 2/20 | 0.40 |
| ▸ | RPL35A | P18077 | 2/20 | 0.40 |
| ▸ | RPL7 | P18124 | 2/20 | 0.40 |
| ▸ | RPL17 | P18621 | 2/20 | 0.40 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.40 |
| ▸ | RPS3 | P23396 | 2/20 | 0.40 |
| ▸ | RPS12 | P25398 | 2/20 | 0.40 |
| ▸ | RPL13 | P26373 | 2/20 | 0.40 |
| ▸ | RPL10 | P27635 | 2/20 | 0.40 |
| ▸ | RPL12 | P30050 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962054 | 0.85 | OPRM1 (0.40) | LMNAOPRM1CDK9SLC6A2SLC6A4 | |
| SCHEMBL4960487 | 0.84 | OPRM1 (0.39) | LMNAOPRM1CDK9SLC6A2SLC6A4 | |
| SCHEMBL4961286 | 0.83 | SLC6A2 (0.50) | LMNAOPRM1CDK9SLC6A2SLC6A4 | |
| SCHEMBL4962814 | 0.82 | CHRM2 (0.52) | LMNACDK9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4963040 | 0.82 | CHRM2 (0.52) | LMNACDK9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4963032 | 0.82 | OPRM1 (0.38) | LMNAOPRM1CDK9SLC6A1SLC6A11 | |
| SCHEMBL4962731 | 0.79 | TRPM8 (0.41) | CDK9SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4961341 | 0.77 | ALDH1A1 (0.55) | LMNASMN1; SMN2 | |
| SCHEMBL4961872 | 0.75 | SLC6A2 (0.46) | LMNACDK9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4960293 | 0.75 | TRPM8 (0.50) | CDK9RPLP1RPLP0RPS17RPSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |