SCHEMBL4962802

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4964462	0.85	KIT (0.64)	RETLCKPLK4AURKAMAPK13
	SCHEMBL4964795	0.79	RIPK1 (0.58)	ANO1IL2RETLCKPLK4
	SCHEMBL5160686	0.77	PTGS1 (0.64)	RETLCKJAK2BTKTLR8
	SCHEMBL30868543	0.77	P2RX1 (0.61)	JAK2PIM1TLR8P2RX1P2RX4
	SCHEMBL4975339	0.76	KDR (0.40)	ANO1RETLCKPLK4AURKA
	SCHEMBL5437515	0.73	TLR8 (0.55)	RETJAK2PIM1TLR8P2RX1
	SCHEMBL17664550	0.72	TLR8 (0.54)	RETJAK2PIM1TLR8P2RX1
	SCHEMBL1829837	0.72	IL2 (0.52)	IL2RETNTRK1TLR8P2RX1
	SCHEMBL16373485	0.71	IL2 (0.69)	ANO1IL2JAK2NTRK1TLR8
	SCHEMBL4962777	0.71	KIT (0.61)	RETLCKPLK4AURKAMAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.