Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988323 | 0.86 | NPC1 (0.59) | KDM4EMEN1KMT2ALTB4R2FFAR1 | |
| SCHEMBL7897886 | 0.84 | NQO1 (0.44) | KDM4EMEN1KMT2APARP10PKM | |
| SCHEMBL9453349 | 0.84 | MEN1 (0.62) | BCAT2MEN1KMT2ALTB4R2LMNA | |
| SCHEMBL4963646 | 0.82 | BCAT2 (0.65) | BCAT2KDM4EMEN1KMT2APARP10 | |
| SCHEMBL4964238 | 0.82 | PARP10 (0.63) | BCAT2PARP10FFAR1FFAR4LMNA | |
| SCHEMBL5878337 | 0.81 | BCAT2 (0.87) | BCAT2KDM4EMEN1KMT2ALTB4R2 | |
| SCHEMBL6013688 | 0.81 | MKNK1 (0.51) | BCAT2MEN1KMT2ALTB4R2RAB9A | |
| SCHEMBL29618430 | 0.81 | BCAT2 (0.54) | BCAT2PARP10LTB4R2FFAR4NPC1 | |
| SCHEMBL6013603 | 0.79 | NQO1 (0.64) | KDM4EMEN1KMT2AFFAR1FFAR4 | |
| SCHEMBL30582476 | 0.79 | BCAT2 (0.83) | BCAT2KDM4EMEN1KMT2ALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954670-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007062230-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-4093648-A | ANTIANAPHYLACTIC AGENTS | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1978-06-06 | — | — | US | disclosed |