Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496682 | 0.78 | EGFR (0.34) | EGFRSRCHDAC4HDAC7HDAC5 | |
| SCHEMBL497361 | 0.77 | CDC25A (0.36) | ALDH1A1KMT2AGAANPSR1LMNA | |
| SCHEMBL6024230 | 0.74 | HDAC4 (0.42) | EGFRSRCHDAC4HDAC7HDAC5 | |
| SCHEMBL31657761 | 0.71 | MAOA (0.40) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6023539 | 0.71 | HDAC4 (0.47) | EGFRSRCHDAC4HDAC7HDAC5 | |
| SCHEMBL6024136 | 0.68 | ALDH1A1 (0.37) | EGFRSRCHDAC4HDAC7HDAC5 | |
| SCHEMBL30392277 | 0.68 | GAA (0.41) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16835542 | 0.67 | GAA (0.40) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL13615629 | 0.67 | MAPT (0.42) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10028545 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106203-B2 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| EP-2096110-B1 | Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase | LUMIGEN INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20090246819-A1 | Assay Methods Using Chemiluminescent Detection of Peroxidase | LUMIGEN, INC. | 2009-10-01 | — | — | US | disclosed |
| EP-2096110-A1 | Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7560556-B2 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| EP-1456176-B1 | IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN INC (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7247726-B2 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-20050158815-A1 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN INC. | 2005-07-21 | — | — | US | disclosed |
| US-6872828-B2 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-6858733-B2 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1456176-A4 | IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1456176-A1 | IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN, INC. (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20040176599-A1 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. | 2004-09-09 | — | — | US | disclosed |
| US-20030170762-A1 | Compounds for generating chemiluminescence with a peroxidase | LUMIGEN, INC. | 2003-09-11 | — | — | US | disclosed |
| US-20030170771-A1 | Compounds for generating chemiluminescence with a peroxidase | AKHAVAN-TAFTI HASHEM (US) | 2003-09-11 | — | — | US | disclosed |
| WO-2003053934-A1 | IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176599-A1 | Compounds for generating chemiluminescence with a peroxidase | LPO, MPO, GPX4 | EGFR 4479/4885SRC 3170/4885HDAC4 4295/4885 |
| US-20030170762-A1 | Compounds for generating chemiluminescence with a peroxidase | LPO, MPO, GPX4 | EGFR 4479/4885SRC 3170/4885HDAC4 4295/4885 |
| US-20030170771-A1 | Compounds for generating chemiluminescence with a peroxidase | LPO, MPO, GPX4 | EGFR 4479/4885SRC 3170/4885HDAC4 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.