Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417469 | 0.82 | MMP1 (0.65) | MMP1RXFP1KMT2ANPC1RAB9A | |
| SCHEMBL9551853 | 0.80 | CHRM3 (0.48) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL13053952 | 0.78 | NPC1 (0.48) | MMP1RXFP1KMT2ANPC1RAB9A | |
| SCHEMBL8623142 | 0.77 | DHODH (0.68) | MMP1RXFP1KMT2ANPC1RAB9A | |
| SCHEMBL6800698 | 0.76 | MLYCD (0.68) | DEGS1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7272760 | 0.76 | MLYCD (0.68) | DEGS1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6163176 | 0.76 | MAPT (0.56) | KMT2ARAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL13053957 | 0.76 | NPC1 (0.46) | MMP1DEGS1RXFP1KMT2ANPC1 | |
| SCHEMBL3753090 | 0.76 | HDAC1 (0.68) | MMP1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28904178 | 0.76 | RAB9A (0.65) | MMP1RXFP1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954670-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007062230-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2007-05-31 | — | — | WO | claimed |