Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 9/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965899 | 0.96 | CXCR3 (0.33) | RORCCXCR3CYP2D6 | |
| SCHEMBL4965081 | 0.87 | OPRM1 (0.36) | RORCCXCR3 | |
| SCHEMBL4966117 | 0.82 | MAPK14 (0.36) | CXCR3CYP2D6 | |
| SCHEMBL4965290 | 0.79 | TRPM8 (0.39) | ACHECXCR3 | |
| SCHEMBL4968562 | 0.76 | HDAC6 (0.45) | — | |
| SCHEMBL14398822 | 0.74 | CXCR3 (0.32) | RORCCXCR3 | |
| SCHEMBL4965646 | 0.74 | OPRM1 (0.41) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL4965277 | 0.73 | OPRM1 (0.41) | CYP2D6 | |
| SCHEMBL4965823 | 0.73 | MEN1 (0.45) | — | |
| SCHEMBL4963719 | 0.73 | MEN1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730140-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-06-25 | — | — | EP | claimed |