Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640534 | 0.89 | — | — | |
| SCHEMBL13713003 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2HIF1AFAAHCA1 | |
| SCHEMBL20851271 | 0.77 | ALDH1A1 (0.35) | LMNAHTR2CHTR2BPDK2 | |
| SCHEMBL8656464 | 0.76 | NOS3 (0.39) | TSHR | |
| SCHEMBL269332 | 0.76 | GABRA1 (0.46) | GABRA1GABRB2HIF1AFAAHCA1 | |
| Ammonia Solution, Strong SCHEMBL28822995 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2HIF1AFAAHCA1 | |
| SCHEMBL6852595 | 0.74 | MMP2 (0.47) | HIF1ACA1CA2LMNACYP1A2 | |
| SCHEMBL4967850 | 0.73 | LMNA (0.39) | GABRA1GABRB2HIF1AFAAHCA1 | |
| Alcohol SCHEMBL27794349 | 0.72 | GABRA1 (0.45) | GABRA1GABRB2HIF1AFAAHCA1 | |
| SCHEMBL12371007 | 0.72 | GABRA1 (0.39) | GABRA1GABRB2HIF1AFAAHCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113835-A1 | PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | disclosed |