SCHEMBL4976890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4977326	0.93	MET (0.49)	NPC1RAB9APDPK1METKDR
	SCHEMBL4974088	0.88	KDR (0.49)	PDPK1METKDR
	SCHEMBL4976457	0.86	KDR (0.47)	NPC1RAB9APDPK1METKDR
	SCHEMBL4979584	0.84	RAB9A (0.47)	NPC1RAB9APDPK1METKDR
	SCHEMBL4973733	0.82	DHPS (0.52)	HTTPDPK1METKDRMEN1
	SCHEMBL4972995	0.82	KDR (0.64)	HTTPDPK1METKDRMEN1
	SCHEMBL4974546	0.81	MET (0.47)	NPC1RAB9AHTTPDPK1MET
	SCHEMBL5417962	0.81	KDR (0.55)	PDPK1METKDRMEN1MAPT
	SCHEMBL4972318	0.80	KDR (0.46)	PDPK1METKDR
	SCHEMBL4974477	0.80	KDR (0.69)	PDPK1METKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.