SCHEMBL4977326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4976890	0.93	NPC1 (0.51)	METPDPK1KDRMEN1NPC1
	SCHEMBL4974088	0.92	KDR (0.49)	METPDPK1KDRCITMAP3K7
	SCHEMBL4974546	0.87	MET (0.47)	METPDPK1KDRMEN1NPC1
	SCHEMBL4976457	0.84	KDR (0.47)	METPDPK1KDRNPC1RAB9A
	SCHEMBL4973733	0.84	DHPS (0.52)	METPDPK1KDRMEN1KMT2A
	SCHEMBL4972995	0.84	KDR (0.64)	METPDPK1KDRMEN1KMT2A
	SCHEMBL4979584	0.83	RAB9A (0.47)	METPDPK1KDRNPC1RAB9A
	SCHEMBL5417962	0.82	KDR (0.55)	METPDPK1KDRMEN1KMT2A
	SCHEMBL4972318	0.82	KDR (0.46)	METPDPK1KDRCITMAP3K7
	SCHEMBL4974477	0.82	KDR (0.69)	METPDPK1KDRCITMAP3K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.