Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4978546 | 0.85 | ALDH1A1 (0.42) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL2162172 | 0.82 | ITGB1 (0.44) | TAS1R3TAS1R1TAS1R2ITGB1ITGA4 | |
| SCHEMBL551661 | 0.82 | ITGB1 (0.44) | TAS1R3TAS1R1TAS1R2ITGB1ITGA4 | |
| SCHEMBL551795 | 0.81 | PBRM1 (0.49) | TAS1R3TAS1R1TAS1R2ITGB1ITGA4 | |
| SCHEMBL4975149 | 0.81 | ITGB1 (0.43) | TAS1R3TAS1R1TAS1R2ITGB1ITGA4 | |
| SCHEMBL550830 | 0.79 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2ITGB1ITGA4 | |
| SCHEMBL1188658 | 0.76 | PTGES (0.41) | — | |
| SCHEMBL16997850 | 0.75 | TP53 (0.42) | RAB9AALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL516136 | 0.75 | TP53 (0.40) | RAB9AALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL196145 | 0.75 | TP53 (0.40) | RAB9AALDH1A1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045727-A1 | Chiral 3-Halophthalic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045727-A1 | Chiral 3-Halophthalic Acid Derivatives | HDHD5, CRYZ, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TAS1R3 4145/4885TAS1R1 4747/4885TAS1R2 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.