SCHEMBL498351

SCHEMBL498351

CCOP(=O)(Cc1cccc(C(=O)OC)c1)OCC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.57
CYP4F2 P78329 3/20 0.56
CYP4A11 Q02928 3/20 0.56
HDAC1 Q13547 1/20 0.51
SLC7A5 Q01650 1/20 0.50
FOLH1 Q04609 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.47
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
HIF1A Q16665 1/20 0.45
HTT P42858 1/20 0.45
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.44
CD74 P04233 1/20 0.44
MIF P14174 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454035 0.89 CYP4F2 (0.58) CYP4F2CYP4A11HDAC1RAB9ASMN1; SMN2
SCHEMBL914873 0.89 LOXL2 (0.57) LOXL2CYP4F2CYP4A11SLC7A5FOLH1
SCHEMBL3475567 0.87 LOXL2 (0.62) LOXL2CYP4F2CYP4A11SLC7A5FOLH1
SCHEMBL8669463 0.85 HDAC1 (0.50) LOXL2CYP4F2CYP4A11HDAC1MRGPRX4
SCHEMBL915153 0.85 MRGPRX4 (0.54) HDAC1FOLH1MRGPRX4RAB9ASMN1; SMN2
SCHEMBL915654 0.85 KDM4E (0.46) LOXL2CYP4F2CYP4A11HDAC1SLC7A5
SCHEMBL23684777 0.85 SLC7A5 (0.53) LOXL2CYP4F2CYP4A11HDAC1SLC7A5
SCHEMBL30260202 0.85 SLC7A5 (0.53) LOXL2CYP4F2CYP4A11HDAC1SLC7A5
SCHEMBL27233594 0.83 FAAH (0.48) HDAC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL10584686 0.83 RAB9A (0.46) LOXL2CYP4F2CYP4A11HDAC1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313546-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2025-10-09 US disclosed
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
EP-4522588-A1 NUCLEIC ACID BINDERS University of Strathclyde (GB) 2025-03-19 EP disclosed
WO-2023218194-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2023-11-16 WO disclosed
CN-110878052-B FXR agonist-containing compound and preparation method and application thereof 山东大学 2021-05-07 CN disclosed
CN-110878052-A FXR agonist-containing compound and preparation method and application thereof 山东大学 2020-03-13 CN disclosed
CN-105884758-A Tricyclic compound and application thereof to drugs 广东东阳光药业有限公司 2016-08-24 CN disclosed
CN-104513213-A Fxr agonist KBP BIOSCIENCES CO LTD 2015-04-15 CN disclosed
US-8952042-B2 FXR (NR1H4) binding and activity modulating compounds PHENEX PHARMACEUTICALS AG (DE) 2015-02-10 US disclosed
US-8952042-B2 FXR (NR1H4) binding and activity modulating compounds PHENEX PHARMACEUTICALS AG (DE) 2015-02-10 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
CN-101263175-A Polyester, process for production of polyester, and polyester molded article TOYO BOSEKI (JP) 2008-09-10 CN disclosed
CN-101208371-A Method for preparing polyester and polyester manufactured by the method as well as polyester formed body TOYO BOSEKI (JP) 2008-06-25 CN disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
WO-2008038018-A1 NOVEL MINOR GROOVE BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2008-04-03 WO disclosed
WO-2007140174-A2 COMPOUNDS AND METHODS FOR MODULATING FXR ELI LILLY AND COMPANY (US) 2007-12-06 WO disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed
US-20010037025-A1 New compounds, their preparation and use MURRAY ANTHONY (DK) 2001-11-01 US disclosed
EP-1077919-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-02-28 EP disclosed
WO-1999058486-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1999-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037025-A1 New compounds, their preparation and use GPR119, SLC5A1, SLC5A2 LOXL2 4024/4885CYP4F2 849/4885CYP4A11 180/4885
US-20250313546-A1 NUCLEIC ACID BINDERS ZFR, NSUN3, POLI LOXL2 4699/4885CYP4F2 4809/4885CYP4A11 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.