Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988175 | 0.86 | AKR1C3 (0.47) | AKR1C3GAAALDH1A1LMNAKMT2A | |
| SCHEMBL4980960 | 0.84 | SMN1; SMN2 (0.46) | FAAHAKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL4989343 | 0.83 | AKR1C3 (0.44) | AKR1C3AKR1C1GAAALDH1A1LMNA | |
| SCHEMBL4988642 | 0.81 | MAPT (0.43) | AKR1C3AKR1C2AKR1C1ALDH1A1LMNA | |
| SCHEMBL5145783 | 0.80 | FAAH (0.40) | FAAHAKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL4992564 | 0.80 | MEN1 (0.47) | AKR1C3AKR1C1GAALMNAMEN1 | |
| SCHEMBL4985245 | 0.80 | LMNA (0.38) | FAAHAKR1C3ALDH1A1LMNAHTT | |
| SCHEMBL4983067 | 0.80 | PKM (0.43) | GAAALDH1A1LMNAMEN1MAPT | |
| SCHEMBL4988448 | 0.80 | MEN1 (0.45) | AKR1C3AKR1C1GAAALDH1A1MEN1 | |
| SCHEMBL4986174 | 0.80 | PKM (0.46) | AKR1C3AKR1C1GAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | RENOVIS, INC. | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | P2RX7, P2RX3, P2RX2 | FAAH 494/4885AKR1C3 1419/4885AKR1C2 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.