Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495428 | 1.00 | MAOB (0.58) | MAOBMAOAALDH1A1CYP3A4HPGD | |
| SCHEMBL11778899 | 0.91 | KCNMA1 (0.51) | MAOBMAOAALDH1A1CYP3A4HPGD | |
| SCHEMBL218964 | 0.83 | CA1 (0.67) | MAOBMAOAHPGDMAPK1CA1 | |
| SCHEMBL27612735 | 0.82 | CA1 (0.54) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL20117002 | 0.82 | ALDH1A1 (0.50) | MAOBMAOAALDH1A1MAPK1CA1 | |
| Bromide SCHEMBL30207997 | 0.81 | CA1 (0.64) | MAOBMAOAHPGDMAPK1CA1 | |
| Hydrochloric Acid SCHEMBL11784623 | 0.81 | CA1 (0.64) | MAOBMAOAHPGDMAPK1CA1 | |
| SCHEMBL29384783 | 0.80 | TSHR (0.65) | ALDH1A1CYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL14439661 | 0.80 | ALDH1A1 (0.48) | MAOBMAOAALDH1A1MAPK1CA1 | |
| SCHEMBL4880939 | 0.80 | CA1 (0.52) | MAOBMAOAALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116515782-A | Amine dehydrogenase mutant and application thereof in chiral amine alcohol compound synthesis | 中国科学院天津工业生物技术研究所 | 2023-08-01 | — | — | CN | claimed |
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | claimed |
| CN-114751870-A | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | claimed |
| EP-3253750-B1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2019-04-10 | — | — | EP | claimed |
| US-10221165-B2 | Flavone based EGFR inhibitors and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-05 | — | — | US | claimed |
| US-20180016268-A1 | Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-01-18 | — | — | US | claimed |
| WO-2016125186-A1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | WO | claimed |
| EP-4660194-A1 | SALT AND CRYSTAL FORM OF CYCLOALKENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2025-12-10 | — | — | EP | disclosed |
| WO-2025217336-A1 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| CN-118638089-B | Preparation method for synthesizing flavonoid compound based on carbon dioxide | 湖南工程学院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118638089-A | Preparation method for synthesizing flavonoid compound based on carbon dioxide | 湖南工程学院 | 2024-09-13 | — | — | CN | disclosed |
| US-20240208986-A1 | PHENYL AZEPINES AS RIPK1 INHIBITORS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | US | disclosed |
| CN-117986264-A | Benzo nitrogen-containing polycyclic derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-4402968-A | Antifungal benzofuranyl imidazole compounds | HOFFMANN-LA ROCHE INC. (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0041673-A1 | Imidazole derivatives, their preparation and compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-12-16 | — | — | EP | disclosed |
| US-4265903-A | HYPOTENSIVE, ADRENOLYTIC | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| US-4122256-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-3994879-A | CONDENSING AZOMETHINES, OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
| US-3933918-A | ANTITUSSIVE | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016268-A1 | Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof | EGFR, ERBB2, ABL1 | MAOB 1112/4885MAOA 1733/4885ALDH1A1 1959/4885 |
| US-20240208986-A1 | PHENYL AZEPINES AS RIPK1 INHIBITORS AND METHODS OF USE THEREOF | RIPK1, RIPK2, RIPK4 | MAOB 3715/4885MAOA 3315/4885ALDH1A1 4049/4885 |
| US-10221165-B2 | Flavone based EGFR inhibitors and process for preparation thereof | EGFR, ERBB2, ABL1 | MAOB 1202/4885MAOA 1685/4885ALDH1A1 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.