Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985341 | 0.77 | CHRNA7 (0.50) | PDE4BMEN1KMT2ACHRNA7 | |
| SCHEMBL11216122 | 0.70 | CHRNA7 (0.40) | CHRNA7 | |
| SCHEMBL3056405 | 0.70 | MAOA (0.62) | PDE4BPDE4APDE4CPDE4DCTSV | |
| SCHEMBL6031474 | 0.69 | EGFR (0.50) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL4988764 | 0.69 | SRD5A1 (0.46) | SRD5A1SRD5A2CHRNA7MAPT | |
| SCHEMBL3041636 | 0.68 | MAOA (0.53) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL16537757 | 0.67 | PDE4A (0.53) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL16536586 | 0.67 | PDE4A (0.53) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL18949798 | 0.67 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL7214919 | 0.66 | SRD5A1 (0.58) | SRD5A1SRD5A2CTSVCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | PDXK, PKD1, GLS | PDE4B 2264/4885PDE4A 2652/4885PDE4C 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.