Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965362 | 1.00 | CPB2 (0.47) | CPB2GGT1KDM4EMAPTTHRB | |
| SCHEMBL94249 | 0.88 | GGT1 (0.56) | CPB2GGT1KDM4EMAPTTHRB | |
| SCHEMBL307700 | 0.88 | GGT1 (0.56) | CPB2GGT1KDM4EMAPTTHRB | |
| SCHEMBL619940 | 0.88 | GGT1 (0.56) | CPB2GGT1KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL1574244 | 0.86 | GGT1 (0.55) | CPB2GGT1KDM4EMAPTTHRB | |
| SCHEMBL900182 | 0.83 | KDM4E (0.54) | GGT1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL900178 | 0.83 | KDM4E (0.54) | GGT1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL17378062 | 0.83 | KDM4E (0.54) | GGT1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL146727 | 0.82 | GGT1 (0.55) | CPB2GGT1RNPEPFOLH1GSR | |
| SCHEMBL6890284 | 0.82 | GGT1 (0.55) | CPB2GGT1RNPEPFOLH1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452704-B2 | Dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7115735-B2 | Dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060205045-A1 | Which produces N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH as coenzyme; biosynthesis | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20050124040-A1 | Novel dehydrogenase and a gene encoding the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-06-09 | — | — | US | disclosed |
| US-5952307-A | Basic α-aminoalkylphosphonate derivatives | GEORGIA TECH RESEARCH CORP. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5686419-A | SERINE PROTEASE INHIBITOR ANTICOAGULANTS | GEORGIA TECH RESEARCH CORP. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0804252-A2 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5543396-A | Proline phosphonate derivatives | GEORGIA TECH RESEARCH CORP. (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1995033497-A1 | MONOAMINE, DIAMIDE, THIOL-CONTAINING METAL CHELATING AGENTS | DIATECH, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995029691-A1 | PROLINE PHOSPHONATE DERIVATIVES | GEORGIA TECH RESEARCH CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205045-A1 | Which produces N-alkyl-L-alanine from pyruvic acid and alkylamine or dialkylamine using NADPH and/or NADH as coenzyme; biosynthesis | ME1, NADK, ME3 | CPB2 1632/4885GGT1 506/4885KDM4E 1504/4885 |
| US-20050124040-A1 | Novel dehydrogenase and a gene encoding the same | ALDH7A1, MDH2, DPYD | CPB2 1823/4885GGT1 548/4885KDM4E 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.