Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5003268 | 0.87 | KDM5A (0.39) | KDM5AKIF11KDM4ELMNACHRNA1 | |
| SCHEMBL5005972 | 0.81 | TAAR1 (0.37) | KDM4ELMNA | |
| SCHEMBL5005996 | 0.79 | HDAC1 (0.40) | KIF11KDM4ELMNAHSD17B10CHRNA1 | |
| SCHEMBL12430133 | 0.76 | CYP17A1 (0.36) | KDM5ACYP17A1KIF11ABCB1KDM4E | |
| SCHEMBL1748028 | 0.73 | CYP17A1 (0.39) | KDM5ACYP17A1KIF11ABCB1ABCC1 | |
| SCHEMBL5006817 | 0.70 | LMNA (0.40) | KDM4ELMNAHSD17B10SLC6A3 | |
| SCHEMBL16539493 | 0.70 | KDM5A (0.67) | KDM5AKDM4ELMNAHSD17B10ERN1 | |
| SCHEMBL5006804 | 0.69 | ALDH1A1 (0.47) | KDM4ELMNACHRNA1CHRNGCHRNB1 | |
| SCHEMBL5438347 | 0.69 | KIF11 (0.60) | KIF11 | |
| SCHEMBL5009253 | 0.68 | CES2 (0.43) | LMNASLC6A2SLC6A3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423156-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |