Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600942 | 0.82 | HCAR3 (0.41) | ALDH1A1PYCR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6505678 | 0.69 | NR1H2 (0.41) | ALDH1A1L3MBTL1KDM4EKMT2AIDO1 | |
| SCHEMBL10941283 | 0.66 | SLC6A2 (0.50) | ALDH1A1L3MBTL1PYCR1SLC6A2SLC6A4 | |
| SCHEMBL15616984 | 0.66 | AOC3 (0.41) | ALDH1A1PYCR1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL19354586 | 0.66 | SLC6A4 (0.41) | ALDH1A1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19354511 | 0.66 | SLC6A4 (0.41) | ALDH1A1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5026313 | 0.66 | IGF1R (0.39) | ALDH1A1L3MBTL1KCNH2 | |
| SCHEMBL11327663 | 0.64 | ALDH1A1 (0.44) | ALDH1A1CHRM2KDM4EMEN1KMT2A | |
| SCHEMBL10821420 | 0.62 | RAB9A (0.38) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL10945992 | 0.62 | SLC6A3 (0.63) | ALDH1A1L3MBTL1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-11300640-B2 | Protein reporters for ultrasensitive detection methods | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-04-12 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190219646-A1 | Protein Reporters for Ultrasensitive Detection Methods | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2019-07-18 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |