Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CALCA | P06881 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201034 | 0.81 | VSIR (0.38) | ALDH1A1GLAVSIRPTPRCLATS1 | |
| SCHEMBL10367814 | 0.81 | MTNR1A (0.38) | ALDH1A1GLAVSIRPTPRCLATS1 | |
| SCHEMBL10367555 | 0.80 | APP (0.36) | ALDH1A1GLAVSIRPTPRCLATS1 | |
| SCHEMBL783009 | 0.73 | CA2 (0.41) | VSIRPTPRCLATS1L3MBTL1GAA | |
| SCHEMBL3720436 | 0.71 | CYP1A1 (0.39) | KDM4E | |
| SCHEMBL3409876 | 0.70 | VSIR (0.46) | ALDH1A1GLAVSIRPTPRCLATS1 | |
| SCHEMBL1278083 | 0.70 | CA12 (0.35) | VSIRPTPRCLATS1L3MBTL1TDP1 | |
| SCHEMBL5004491 | 0.69 | NR1D1 (0.34) | ALDH1A1GLAGABRA1GABRG2GABRB3 | |
| SCHEMBL14721489 | 0.68 | PSEN1 (0.43) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7433191 | 0.68 | CA12 (0.50) | PTPRCKDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305049-A1 | Mri Contrast Agents for Diagnosis and Prognosis of Tumors | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 2008-12-11 | — | — | US | disclosed |
| EP-1848466-A2 | MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006080022-A2 | MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305049-A1 | Mri Contrast Agents for Diagnosis and Prognosis of Tumors | TFRC, FOLR1, CD14 | ALDH1A1 4392/4885GLA 3498/4885VSIR 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.