Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.65 |
| ▸ | CA2 | P00918 | 5/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.57 |
| ▸ | PDE4A | P27815 | 10/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135328 | 0.84 | CA1 (0.65) | CA1CA2CA12CA9CA4 | |
| An-2718 SCHEMBL5583381 | 0.82 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| An-2718 SCHEMBL500874 | 0.82 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL564776 | 0.81 | CA1 (0.43) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL10268396 | 0.78 | CA1 (0.62) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL499992 | 0.78 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL5583348 | 0.78 | PDE4B (0.69) | CA1CA2PDE3APDE4BPDE4A | |
| Tavaborole SCHEMBL500016 | 0.78 | CA1 (1.00) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL10220172 | 0.78 | CA1 (0.62) | CA1CA2PDE3APDE4BPDE4A | |
| SCHEMBL14473060 | 0.78 | CA1 (0.62) | CA1CA2PDE3APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260218-A | Preparation method of clilboro | 安庆百谊生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-3971191-A1 | BORON-CONTAINING SMALL MOLECULES | Bill And Melinda Gates Foundation (US) | 2022-03-23 | — | — | EP | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| US-11091504-B2 | Process for the preparation of tavaborole, its novel polymorphic forms and the polymorphs thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-08-17 | — | — | US | disclosed |
| EP-3423065-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2021-07-21 | — | — | EP | disclosed |
| US-10919916-B2 | Boron-containing small molecules | BILL & MELINDA GATES FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BILL & MELINDA GATES FOUNDATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10611780-B2 | Boron-containing small molecules | BILL AND MELINDA GATES FOUNDATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-20200087325-A1 | Novel Process for the Preparation of Tavaborole, Its Novel Polymorphic Forms and the Polymorphs Thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-03-19 | — | — | US | disclosed |
| US-10435419-B2 | Process for the preparation of tavaborole, its novel polymorphic forms and the polymorphs thereof | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-10-08 | — | — | US | disclosed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011094450-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC (US) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011094450-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC (US) | 2011-08-04 | — | — | WO | disclosed |
| EP-2187893-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087325-A1 | Novel Process for the Preparation of Tavaborole, Its Novel Polymorphic Forms and the Polymorphs Thereof | VKORC1L1, VPS4B, HLA-B | CA1 4520/4885CA2 4453/4885PDE3A 3861/4885 |
| US-11091504-B2 | Process for the preparation of tavaborole, its novel polymorphic forms and the polymorphs thereof | HLA-B, VKORC1L1, VPS4B | CA1 4579/4885CA2 4423/4885PDE3A 3861/4885 |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | NFKBIA, LITAF, CD68 | CA1 1538/4885CA2 829/4885PDE3A 1691/4885 |
| US-10919916-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | CA1 3591/4885CA2 743/4885PDE3A 1953/4885 |
| US-10611780-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | CA1 3591/4885CA2 743/4885PDE3A 1953/4885 |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | CA1 3591/4885CA2 743/4885PDE3A 1953/4885 |
| US-10435419-B2 | Process for the preparation of tavaborole, its novel polymorphic forms and the polymorphs thereof | HLA-B, VKORC1L1, VPS4B | CA1 4579/4885CA2 4423/4885PDE3A 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.