SCHEMBL5009528

SCHEMBL5009528

C=CCc1sccc1S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630114 0.76 KEAP1 (0.33) NPSR1POLBALOX5PTGS1PTGS2
SCHEMBL11837969 0.73 LMNA (0.32) NPSR1LMNA
SCHEMBL4787280 0.71 POLB (0.40) NPSR1POLBTDP1ALOX5PTGS1
SCHEMBL628655 0.71
SCHEMBL3801503 0.69 KMT2A (0.40) NPSR1POLBTDP1ALDH1A1KMT2A
SCHEMBL1164626 0.69 GABRA1 (0.36) POLBALOX5PTGS1PTGS2
SCHEMBL1101287 0.67
SCHEMBL8621364 0.67
SCHEMBL1205997 0.67
SCHEMBL3630092 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371873-B2 Sulfoxyalkylthiophene and process for producing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-05-13 US disclosed
US-20070260071-A1 Sulfoxyalkylthiophene and Process for Producing the Same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-11-08 US disclosed
EP-1693370-A1 SULFOXYALKYLTHIOPHENE COMPOUND AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2006-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070260071-A1 Sulfoxyalkylthiophene and Process for Producing the Same TST, SULT1A1, MPST NPSR1 1930/4885POLB 2515/4885TDP1 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.