SCHEMBL5012011

SCHEMBL5012011

CO[Si](OC)(OC)c1ccc(CCCNCCN)cc1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.43
DRD2 P14416 2/20 0.40
DRD4 P21917 2/20 0.40
DRD3 P35462 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9176047 0.83 CHRM2 (0.45)
SCHEMBL37363 0.81 TAAR1 (0.55)
SCHEMBL8813462 0.76 CHRM2 (0.33)
SCHEMBL28063476 0.76 TAAR1 (0.36) SIGMAR1
SCHEMBL2464561 0.75 CA2 (0.46)
SCHEMBL8759913 0.75 CHRM2 (0.30)
SCHEMBL18938582 0.75 CHRM2 (0.33)
SCHEMBL2953186 0.74 CALM1 (0.35)
SCHEMBL5485012 0.74 ALDH1A1 (0.50)
SCHEMBL2945374 0.74 CALM1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7329716-B2 Siloxane oligomers by phase transfer catalysis YAZAKI CORPORATION (JP) 2008-02-12 US disclosed
US-7329715-B2 Abrasion resistant coatings by siloxane oligomers YAZAKI CORPORATION (JP) 2008-02-12 US disclosed
US-20060235179-A1 Siloxane oligomers by phase transfer catalysis YAZAKI CORPORATION (JP) 2006-10-19 US disclosed
US-20060235178-A1 Abrasion resistant coatings by siloxane oligomers STOWE WOODWARD LLC 2006-10-19 US disclosed