SCHEMBL816636

SCHEMBL816636

CCCCC[C](C)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
PTGS2 P35354 4/20 0.52
NAAA Q02083 1/20 0.46
ALDH1A1 P00352 1/20 0.45
LMNA P02545 2/20 0.44
ESR1 P03372 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18045476 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL1581395 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL11494540 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL19642160 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL5968483 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL815938 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL2761831 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL4453742 0.98 CES2 (0.59) CES2CES1PTGS2NAAALMNA
SCHEMBL820442 0.93 PTGS2 (0.59) CES2CES1PTGS2NAAAALDH1A1
SCHEMBL3281895 0.86 L3MBTL1 (0.44) CES2CES1PTGS2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
CN-1555362-A Process for producing dialkyl peroxide 日本油脂株式会社 2004-12-15 CN claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-10807946-B2 Antagonists of the glucagon receptor METABASIS THERAPEUTICS, INC. (US) 2020-10-20 US disclosed
US-10662259-B2 Glycogen-based water solubility enhancers AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2020-05-26 US disclosed
EP-2981557-B1 GLYCOGEN-BASED WATER SOLUBILITY ENHANCERS ACRAF (IT) 2020-02-05 EP disclosed
US-20190218176-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2019-07-18 US disclosed
US-10239829-B2 Antagonists of the glucagon receptor METABASIS THERAPEUTICS, INC. (US) 2019-03-26 US disclosed
US-20170275246-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR METABASIS THERAPEUTICS, INC. 2017-09-28 US disclosed
US-9701626-B2 Antagonists of the glucagon receptor METABASIS THERAPEUTICS, INC. (US) 2017-07-11 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662259-B2 Glycogen-based water solubility enhancers GYS2, GYS1, PYGL CES2 348/4885CES1 266/4885PTGS2 2959/4885
US-20190218176-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR GLP1R, GCGR, GPR119 CES2 4048/4885CES1 1202/4885PTGS2 2257/4885
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 CES2 4281/4885CES1 4486/4885PTGS2 3242/4885
US-10239829-B2 Antagonists of the glucagon receptor GLP1R, GCGR, GPR119 CES2 3982/4885CES1 1287/4885PTGS2 2534/4885
US-20170275246-A1 NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR GLP1R, GCGR, GPR119 CES2 4023/4885CES1 1170/4885PTGS2 2305/4885
US-10807946-B2 Antagonists of the glucagon receptor GLP1R, GCGR, GPR119 CES2 3998/4885CES1 1294/4885PTGS2 2521/4885
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B CES2 3633/4885CES1 4368/4885PTGS2 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.