Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011764 | 0.90 | HTT (0.44) | HPGDL3MBTL1CNR1CNR2HTT | |
| SCHEMBL5066934 | 0.74 | KMT2A (0.35) | CNR1CNR2LMNATHRB | |
| SCHEMBL1086498 | 0.73 | HPGD (0.46) | HPGDCCR5 | |
| SCHEMBL5011708 | 0.67 | CYP1A2 (0.45) | HPGDL3MBTL1HTTLMNATHRB | |
| SCHEMBL5012930 | 0.66 | CNR2 (0.38) | HPGDCNR1CNR2 | |
| SCHEMBL5011747 | 0.66 | KCNK3 (0.40) | HPGDLMNA | |
| SCHEMBL5011879 | 0.65 | KMT2A (0.38) | HPGDLMNA | |
| SCHEMBL5011651 | 0.64 | CHRM2 (0.44) | L3MBTL1LMNA | |
| SCHEMBL5060789 | 0.64 | PTPN1 (0.41) | — | |
| SCHEMBL5016389 | 0.63 | ALDH1A1 (0.35) | L3MBTL1HTTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910381-A2 | SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]-DECAN-2-ON- COMPOUNDS AND THE USE THEREOF FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007000325-A2 | SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]-DECAN-2-ON- COMPOUNDS AND THE USE THEREOF FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2007-01-04 | — | — | WO | disclosed |