Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD4 | P21917 | 6/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013346 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1POLBTSHRMEN1 | |
| SCHEMBL5016133 | 0.84 | KMT2A (0.51) | KDM4EALDH1A1POLBTSHRMEN1 | |
| SCHEMBL2095285 | 0.81 | SMN1; SMN2 (0.34) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5015080 | 0.79 | DRD2 (0.41) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5015111 | 0.77 | GNRHR (0.44) | KDM4EALDH1A1POLBTSHRMEN1 | |
| SCHEMBL27666126 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1POLBTSHRMEN1 | |
| SCHEMBL5013459 | 0.76 | MEN1 (0.52) | ALDH1A1MEN1KMT2ABCHEDRD2 | |
| SCHEMBL2094075 | 0.74 | SCD (0.36) | TSHRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2090169 | 0.70 | GRIN2B (0.42) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL5016131 | 0.70 | ALDH1A1 (0.51) | KDM4EALDH1A1POLBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |