Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016131 | 0.86 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EPOLBBCHE | |
| SCHEMBL5015111 | 0.84 | GNRHR (0.44) | KMT2AALDH1A1KDM4EPOLBBCHE | |
| SCHEMBL5013348 | 0.84 | KDM4E (0.45) | KMT2AALDH1A1KDM4EPOLBBCHE | |
| SCHEMBL2090169 | 0.82 | GRIN2B (0.42) | KMT2ABCHEACHETSHRMEN1 | |
| SCHEMBL27644481 | 0.78 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL5015080 | 0.77 | DRD2 (0.41) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL5013459 | 0.77 | MEN1 (0.52) | KMT2AALDH1A1BCHEMEN1CASP1 | |
| SCHEMBL27666519 | 0.76 | POLB (0.64) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL2093656 | 0.73 | SCD (0.44) | TSHRNPC1RAB9A | |
| SCHEMBL5015107 | 0.71 | GNRHR (0.44) | KMT2AALDH1A1KDM4EPOLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |