Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015079 | 0.86 | DRD2 (0.41) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL2097140 | 0.82 | MAPT (0.38) | MEN1KMT2AL3MBTL1KDM4EGAA | |
| SCHEMBL5013348 | 0.79 | KDM4E (0.45) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL28758331 | 0.78 | DRD4 (0.45) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL5016133 | 0.77 | KMT2A (0.51) | DRD4DRD3MEN1NPC1RAB9A | |
| SCHEMBL5013459 | 0.77 | MEN1 (0.52) | DRD2MEN1KMT2AALDH1A1 | |
| SCHEMBL2088110 | 0.76 | HRH1 (0.37) | RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5015111 | 0.73 | GNRHR (0.44) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL27645184 | 0.69 | DRD2 (0.48) | DRD2DRD4DRD3MAPT | |
| SCHEMBL2097137 | 0.69 | MAPT (0.38) | MEN1KMT2AL3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |