Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29103888 | 0.77 | CA2 (0.47) | AKR1B1ALDH1A1MAPTHPGDCA1 | |
| SCHEMBL16568799 | 0.76 | NPC1 (0.32) | ALDH1A1MAPTHPGDLMNAHTT | |
| SCHEMBL12854186 | 0.74 | PSIP1 (0.32) | — | |
| SCHEMBL6820319 | 0.73 | HTR6 (0.48) | AKR1B1ALDH1A1MAPTLMNAHTT | |
| SCHEMBL2767017 | 0.69 | ALDH1A1 (0.56) | AKR1B1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL5364511 | 0.69 | ALDH1A1 (0.56) | AKR1B1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL11480923 | 0.69 | LMNA (0.36) | ALDH1A1HPGDLMNAHTTKMT2A | |
| SCHEMBL4933821 | 0.69 | AKR1B1 (0.47) | AKR1B1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL31171042 | 0.69 | DAO (0.48) | AKR1B1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7687591 | 0.68 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188079-A1 | METAL-POLISHING COMPOSITION AND CHEMICAL MECHANICAL POLISHING METHOD BY USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-08-07 | — | — | US | disclosed |