SCHEMBL5014207

SCHEMBL5014207

COc1c(OC)c(-c2ccccc2)n(-c2ccc(C)cc2)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
ALDH1A1 P00352 4/20 0.45
RAB9A P51151 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TUBB4A P04350 2/20 0.44
TUBB P07437 2/20 0.44
TUBA3C P0DPH7 2/20 0.44
TUBA1B P68363 2/20 0.44
TUBA4A P68366 2/20 0.44
TUBB4B P68371 2/20 0.44
TUBB3 Q13509 2/20 0.44
TUBB2A Q13885 2/20 0.44
TUBB8 Q3ZCM7 2/20 0.44
TUBA3E Q6PEY2 2/20 0.44
TUBA1A Q71U36 2/20 0.44
TUBA1C Q9BQE3 2/20 0.44
TUBB6 Q9BUF5 2/20 0.44
TUBB2B Q9BVA1 2/20 0.44
TUBB1 Q9H4B7 2/20 0.44
KDM4E B2RXH2 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012020 0.81 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E
SCHEMBL5010847 0.80 HTT (0.51) SMN1; SMN2ALDH1A1RAB9ANPSR1TUBB4A
SCHEMBL445355 0.79 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E
SCHEMBL5012008 0.79 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD
SCHEMBL13997139 0.75 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E
SCHEMBL23665412 0.74 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD
SCHEMBL13997263 0.72 HTT (0.54) SMN1; SMN2ALDH1A1RAB9AKDM4EHPGD
SCHEMBL443060 0.71 LMNA (0.57) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E
SCHEMBL12103552 0.71 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E
SCHEMBL5010875 0.71 MAPK1 (0.59) SMN1; SMN2ALDH1A1RAB9ANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed