Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015080 | 0.86 | DRD2 (0.41) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL2097137 | 0.82 | MAPT (0.38) | MEN1KMT2AL3MBTL1MAPTNPSR1 | |
| SCHEMBL5013346 | 0.79 | KDM4E (0.45) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL28758331 | 0.78 | DRD4 (0.45) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL5016131 | 0.77 | ALDH1A1 (0.51) | DRD4DRD3MEN1NPC1RAB9A | |
| SCHEMBL5016197 | 0.77 | DRD2 (0.43) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL2088107 | 0.76 | HRH1 (0.37) | MAPT | |
| SCHEMBL5015107 | 0.73 | GNRHR (0.44) | DRD2DRD4DRD3MEN1NPC1 | |
| SCHEMBL5011693 | 0.72 | ADRA1A (0.45) | DRD2MAPTTDP1SIGMAR1HTR1A | |
| SCHEMBL5011767 | 0.70 | HRH3 (0.45) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |