SCHEMBL501539

SCHEMBL501539

CN1C(C)(C)CC(C(CCCC(OC(=O)CC(=O)O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.32
KCNH2 Q12809 1/20 0.32
CACNA1A O00555 1/20 0.31
CACNA2D1 P54289 1/20 0.31
CACNB1 Q02641 1/20 0.31
VCAM1 P19320 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759193 0.80 IDH1 (0.33) KCNH2CACNA1ACACNA2D1CACNB1
SCHEMBL5699626 0.78 GPR55 (0.40) GPR55VCAM1
SCHEMBL28550366 0.76
SCHEMBL29612236 0.76 GAA (0.34)
SCHEMBL697947 0.76 ALDH1A1 (0.33) VCAM1
SCHEMBL1345179 0.75 IDH1 (0.33) GPR55KCNH2CACNA1ACACNA2D1CACNB1
SCHEMBL207800 0.75 ALDH1A1 (0.36) KCNH2CACNA1ACACNA2D1CACNB1
SCHEMBL19118382 0.74 HMGCR (0.35) KCNH2VCAM1
SCHEMBL1695282 0.74 HMGCR (0.36) KCNH2
SCHEMBL1695280 0.73 HMGCR (0.37) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0090530-B1 NON-YELLOWING POLYMER COMPOSITION THE DOW CHEMICAL COMPANY (US) 1988-06-01 EP claimed
US-20250046528-A1 ELECTROLYTIC CAPACITOR AND LIQUID COMPONENT FOR ELECTROLYTIC CAPACITOR PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-02-06 US disclosed
WO-2023218994-A1 OPTICAL STYRENE-BASED RESIN COMPOSITION, LIGHTGUIDE PLATE, EDGE-LIGHT SYSTEM FLAT-SURFACE LIGHT SOURCE UNIT, LIGHT DIFFUSION PLATE, AND DIRECT UNDER-LIGHT SYSTEM FLAT-SURFACE LIGHT SOURCE UNIT デンカ株式会社 2023-11-16 WO disclosed
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-8105504-B2 Stabilization of organic materials BASF SE (DE) 2012-01-31 US disclosed
US-20070257234-A1 Stabilization of Organic Materials CIBA CORPORATION 2007-11-08 US disclosed
EP-1110999-A2 Stabilizing mixtures for organic polymers Great Lakes Chemical (Europe) GmbH (CH) 2001-06-27 EP disclosed
US-5283273-A With sterically hindered amine; zinc, calcium, magnesium and/or barium compound; a 1,3-dicarbonyl compound: no organotin or hydrotalcite compounds and no blowing or foaming agents CIBA-GEIGY CORPORATION (US) 1994-02-01 US disclosed
US-5198130-A Zinc thiophosphates, tetramethylpiperidine derivatives CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
EP-0090530-B1 NON-YELLOWING POLYMER COMPOSITION THE DOW CHEMICAL COMPANY (US) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M GPR55 1713/4885KCNH2 3797/4885CACNA1A 4856/4885
US-20070257234-A1 Stabilization of Organic Materials LPO, SOD1, GPX1 GPR55 4053/4885KCNH2 4451/4885CACNA1A 3918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.