Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492282 | 0.81 | CYP2D6 (0.59) | CYP1A2CYP2D6KDM4EPDE4ASMN1; SMN2 | |
| SCHEMBL12409185 | 0.79 | CHRNB2 (0.54) | CYP2D6MAOBATP4AATP4BLTA4H | |
| SCHEMBL26035837 | 0.78 | PSEN1 (0.46) | FAAHCYP2D6RHOCRHOAATP4A | |
| SCHEMBL5016257 | 0.77 | CHRNB2 (0.47) | FAAHMAOBRHOCRHOALTA4H | |
| SCHEMBL28423723 | 0.76 | NR5A1 (0.56) | CYP2D6ATP4AATP4BLTA4HTSHR | |
| SCHEMBL6002773 | 0.76 | RHOC (0.48) | FAAHL3MBTL1MAOBRHOCRHOA | |
| SCHEMBL6002774 | 0.76 | FAAH (0.46) | FAAHSMN1; SMN2RHOCRHOALTA4H | |
| SCHEMBL16961046 | 0.76 | FAAH (0.42) | FAAHCYP2D6L3MBTL1LTA4HALOX5 | |
| SCHEMBL18758480 | 0.75 | FAAH (0.43) | FAAHCYP2D6L3MBTL1ATP4AATP4B | |
| SCHEMBL18758592 | 0.75 | FAAH (0.45) | FAAHCYP2D6L3MBTL1ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |