Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088414 | 0.84 | FAAH (0.48) | FAAHSLC2A1PTGESALOX5PPARG | |
| SCHEMBL6002560 | 0.84 | FAAH (0.48) | FAAHSLC2A1PTGESALOX5PPARG | |
| SCHEMBL12409185 | 0.77 | CHRNB2 (0.54) | PPARALTA4H | |
| SCHEMBL16953374 | 0.77 | FAAH (0.41) | FAAHPTGESALOX5PPARGPPARA | |
| SCHEMBL11398112 | 0.76 | LTA4H (0.61) | FAAHSLC2A1PSMB1PSMB5LTA4H | |
| SCHEMBL26035837 | 0.76 | PSEN1 (0.46) | FAAHPTGESALOX5PPARGPPARA | |
| SCHEMBL5016258 | 0.76 | FAAH (0.48) | FAAHALOX5PPARGRHOCRHOA | |
| SCHEMBL6336026 | 0.75 | PSMB1 (0.54) | PSMB1PSMB5LTA4H | |
| SCHEMBL5016257 | 0.75 | CHRNB2 (0.47) | FAAHPTGESALOX5PPARGPPARA | |
| SCHEMBL12204146 | 0.74 | SMN1; SMN2 (0.50) | SLC2A1PSMB1PSMB5LTA4HMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |