Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422901 | 0.90 | THRB (0.46) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL5014840 | 0.82 | PCNA (0.44) | ALDH1A1THRBCYP3A4SMN1; SMN2PCNA | |
| SCHEMBL5022997 | 0.81 | THRB (0.39) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL4435044 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL5024604 | 0.76 | TUBB4A (0.50) | ALDH1A1MEN1THRBKMT2ATUBB4A | |
| SCHEMBL5024605 | 0.73 | TUBB4A (0.43) | ALDH1A1MAPTMEN1KMT2ATUBB4A | |
| SCHEMBL578049 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL13403404 | 0.70 | PTGS2 (0.46) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL8425480 | 0.70 | PCNA (0.48) | THRBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7144114 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030892-A2 | DRUG DESIGN FOR TUBULIN INHIBITORS, COMPOSITIONS, AND METHODS OF TREATMENT THEREOF | BIPAR SCIENCES, INC. (US) | 2008-03-13 | — | — | WO | disclosed |