Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.50 |
| ▸ | TUBB | P07437 | 3/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.50 |
| ▸ | PCNA | P12004 | 10/20 | 0.47 |
| ▸ | THRB | P10828 | 7/20 | 0.47 |
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422901 | 0.84 | THRB (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5014840 | 0.82 | PCNA (0.44) | PCNATHRBTHRALMNAPOLB | |
| SCHEMBL5024605 | 0.80 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5022997 | 0.79 | THRB (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4422896 | 0.78 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5016597 | 0.76 | ALDH1A1 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3390749 | 0.75 | GAA (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13403404 | 0.74 | PTGS2 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13518328 | 0.73 | TUBB1 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8916819 | 0.72 | TRPV1 (0.49) | LMNAARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030892-A2 | DRUG DESIGN FOR TUBULIN INHIBITORS, COMPOSITIONS, AND METHODS OF TREATMENT THEREOF | BIPAR SCIENCES, INC. (US) | 2008-03-13 | — | — | WO | disclosed |