Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.39 |
| ▸ | PCNA | P12004 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422901 | 0.91 | THRB (0.46) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL4435036 | 0.90 | LMNA (0.48) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL4426971 | 0.90 | LMNA (0.48) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL5016597 | 0.81 | ALDH1A1 (0.46) | THRBPCNAMEN1KMT2ANPSR1 | |
| SCHEMBL4435044 | 0.80 | ALDH1A1 (0.47) | THRBLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5024604 | 0.79 | TUBB4A (0.50) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL5023003 | 0.78 | PCNA (0.45) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL14277457 | 0.76 | THRB (0.41) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL4422896 | 0.76 | TUBB4A (0.52) | THRBPCNALMNAMEN1KMT2A | |
| SCHEMBL5014840 | 0.74 | PCNA (0.44) | THRBPCNALMNATHRAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008030892-A2 | DRUG DESIGN FOR TUBULIN INHIBITORS, COMPOSITIONS, AND METHODS OF TREATMENT THEREOF | BIPAR SCIENCES, INC. (US) | 2008-03-13 | — | — | WO | disclosed |