SCHEMBL501785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL502324	0.95	HPGD (0.61)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL501603	0.90	KDM4E (0.66)	HPGDKDM4EHSD17B10PIN1ALDH1A1
	SCHEMBL501349	0.88	HPGD (0.56)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL14369849	0.88	HPGD (0.56)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL14369858	0.86	HPGD (0.60)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL501463	0.86	HPGD (0.69)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL14369854	0.85	KDM4E (0.62)	HPGDKDM4EHSD17B10PIN1ALDH1A1
	SCHEMBL501298	0.83	PIN1 (0.57)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL14369855	0.83	SIRT2 (0.58)	HPGDKDM4EHSD17B10PDE6DPIN1
	SCHEMBL501712	0.81	HPGD (0.70)	HPGDKDM4EHSD17B10PDE6DPIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.