Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470256 | 0.85 | NR1H4 (0.39) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| SCHEMBL572273 | 0.76 | NR1H4 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL17963718 | 0.76 | NR1H4 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| (3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL30217561 | 0.75 | PTPN1 (0.61) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| (3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL572272 | 0.75 | PTPN1 (0.61) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| (3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL17963716 | 0.75 | PTPN1 (0.61) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| SCHEMBL6850499 | 0.75 | ALOX15 (0.49) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| SCHEMBL28316491 | 0.72 | PTPN1 (0.48) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| SCHEMBL31525286 | 0.71 | HTR2B (0.43) | ALDH1A1HPGDCYP3A4MAPTMAPK1 | |
| SCHEMBL966448 | 0.69 | RIPK1 (0.50) | ALDH1A1HPGDLMNAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106146-B2 | Therapeutic polymers and methods of generation | MEDTRONIC, INC. (US) | 2012-01-31 | — | — | US | claimed |
| US-20110082266-A1 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION | MEDTRONIC, INC. | 2011-04-07 | — | — | US | claimed |
| US-8106146-B2 | Therapeutic polymers and methods of generation | MEDTRONIC, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20110082266-A1 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION | MEDTRONIC, INC. | 2011-04-07 | — | — | US | disclosed |
| US-7462478-B2 | isolated from licorice; catalyzes a dehydration reaction of 2-hydroxy hisoflavanone | NIHON UNIVERSITY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20070050865-A1 | Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same | NIHON UNIVERSITY (JP) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082266-A1 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION | OGFR, OAT, ALK | ALDH1A1 843/4885HPGD 2027/4885CYP3A4 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.