Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850499 | 0.75 | ALOX15 (0.49) | RIPK1LMNAALDH1A1HPGDRELA | |
| SCHEMBL12502194 | 0.73 | MAOB (0.68) | MAOBMAOAHTR2BTMEM97SIGMAR1 | |
| SCHEMBL281853 | 0.71 | MAOB (0.57) | MAOBMAOAHTR2BTMEM97SIGMAR1 | |
| SCHEMBL9748619 | 0.71 | MAOB (0.69) | MAOBMAOACA2CA5AHRH3 | |
| SCHEMBL16179215 | 0.70 | LMNA (0.54) | MAOBMAOALMNANPC1RAB9A | |
| SCHEMBL5851952 | 0.70 | KDM1A (0.54) | MAOBMAOAHRH3NPC1RAB9A | |
| SCHEMBL11716170 | 0.70 | RIPK1 (0.45) | RIPK1MAOBMAOALMNANPC1 | |
| SCHEMBL12469960 | 0.70 | MAOB (0.67) | MAOBMAOACA2CA5AHRH3 | |
| SCHEMBL501806 | 0.69 | ALDH1A1 (0.41) | MAOBHTR2BSIGMAR1LMNANPC1 | |
| SCHEMBL21326806 | 0.69 | MAOB (0.51) | MAOBMAOACA2CA5AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | CYP11B1, CYP2E1, CYP1B1 | RIPK1 3111/4885MAOB 80/4885MAOA 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.