Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966448 | 0.75 | RIPK1 (0.50) | SMN1; SMN2HPGDALDH1A1LMNARELA | |
| SCHEMBL501806 | 0.75 | ALDH1A1 (0.41) | ALOX15ALOX12SMN1; SMN2CYP3A4HSD17B10 | |
| SCHEMBL20790324 | 0.69 | CHRNA1 (0.47) | SMN1; SMN2CYP3A4CYP2C19HSD17B10MEN1 | |
| SCHEMBL28299186 | 0.67 | OPRM1 (0.58) | SMN1; SMN2HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL5046292 | 0.66 | CHRNA1 (0.45) | SMN1; SMN2CYP3A4CYP2C19HSD17B10MEN1 | |
| SCHEMBL10562731 | 0.66 | ALOX15 (1.00) | ALOX15ALOX12CYP1A2KMT2AKDM1A | |
| SCHEMBL29262933 | 0.64 | OPRM1 (0.46) | SMN1; SMN2CYP3A4CYP2C19HSD17B10MEN1 | |
| SCHEMBL31691364 | 0.64 | CHRNA1 (0.43) | SMN1; SMN2CYP3A4CYP2C19HSD17B10MEN1 | |
| SCHEMBL10319703 | 0.64 | OPRM1 (0.55) | SMN1; SMN2HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL12317609 | 0.64 | OPRM1 (0.55) | CYP3A4CYP2C19HSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977578-B1 | COMPOSITIONS TO ENHANCE THE CYTOPROTECTIVE EFFECTS OF POLYCYCLIC PHENOLIC COMPOUNDS THROUGH THE SYNERGISTIC INTERACTION WITH ANTI-OXIDANTS | UNIV FLORIDA (US) | 2004-03-31 | — | — | EP | disclosed |