SCHEMBL501948

SCHEMBL501948

Cc1c(C(=O)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)cc(C(C)(C)C)c(O)c1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.45
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
NR5A2 O00482 1/20 0.33
NR5A1 Q13285 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALOX5 P09917 3/20 0.33
PTGS2 P35354 3/20 0.33
POLB P06746 2/20 0.33
NR1H4 Q96RI1 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
GLRA3 O75311 1/20 0.32
GLRB P48167 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA2 P00918 1/20 0.32
TYR P14679 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995615 0.90 APEX1 (0.46) APEX1MAPTNPSR1NR5A2NR5A1
SCHEMBL30197305 0.83 APEX1 (0.44) APEX1MAPTNPSR1NR5A2NR5A1
SCHEMBL23668727 0.83 APEX1 (0.44) APEX1MAPTNPSR1NR5A2NR5A1
SCHEMBL450851 0.83 APEX1 (0.49) APEX1MAPTNPSR1NR5A2NR5A1
SCHEMBL11205006 0.82 APEX1 (0.46) APEX1MAPTNPSR1CYP2C19ALOX5
SCHEMBL31625511 0.82 APEX1 (0.46) APEX1MAPTNPSR1CYP2C19POLB
SCHEMBL28715272 0.81 NR5A2 (0.36) NR5A2NR5A1CYP2C19ALOX5PTGS2
SCHEMBL27293873 0.80 APEX1 (0.46) APEX1MAPTNPSR1POLBNR1H4
SCHEMBL29850869 0.79 APEX1 (0.48) APEX1MAPTNPSR1CYP2C19POLB
SCHEMBL5685533 0.79 APEX1 (0.48) APEX1MAPTNPSR1CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084104-A1 ADDITIVE MIXTURES BASF SE (DE) 2024-03-14 US disclosed
US-11680343-B2 Textiles and articles, and processes for making the same NIKE, INC. (US) 2023-06-20 US disclosed
US-11021585-B2 Light stabilized polyolefin films, tapes and monofilaments BASF SE (DE) 2021-06-01 US disclosed
US-10864676-B2 Methods of manufacturing articles utilizing foam particles NIKE, INC. (US) 2020-12-15 US disclosed
US-20200223996-A1 LIGHT STABILIZED POLYOLEFIN FILMS, TAPES AND MONOFILAMENTS BASF SE (DE) 2020-07-16 US disclosed
US-10428204-B2 Polyolefin compositions for building materials BASF SE (DE) 2019-10-01 US disclosed
US-20180345576-A1 METHODS OF MANUFACTURING ARTICLES UTILIZING FOAM PARTICLES NIKE, INC. 2018-12-06 US disclosed
US-20180125165-A1 TEXTILES AND ARTICLES, AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2018-05-10 US disclosed
US-20160244591-A1 POLYOLEFIN COMPOSITIONS FOR BUILDING MATERIALS BASF SE (DE) 2016-08-25 US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
US-20080194731-A1 Antimicrobial Polymer Compositions Having Improved Discoloration Resistance CIBA SPECIALTY CHEMICALS CORP. 2008-08-14 US disclosed
US-20080157025-A1 Long Wavelength Shifted Benzotriazole Uv-Absorbers And Their Use CIBA SPECIALTY CHEMICALS CORP. 2008-07-03 US disclosed
US-20080146742-A1 Functionalized Esters, Amides or Urethanes of Perfluorinated Alcohols or Amines as Surface Modifiers CIBA SPECIALY CHEMICALS CORP. 2008-06-19 US disclosed
US-20080096115-A1 Oxime Ester Photoinitiators CIBA SPECIALTY CHEMICALS CORP. 2008-04-24 US disclosed
US-20070257234-A1 Stabilization of Organic Materials CIBA CORPORATION 2007-11-08 US disclosed
US-20070244233-A1 Adding metal alcoholate such as zinc glycerolate to homopolymer or copolymer of propylene; resistance to anisotropic shrinkage CIBA SPECIALTY CHEMICALS CORP. 2007-10-18 US disclosed
EP-1727858-A1 COUPLING AGENTS BETWEEN FILLER AND ELASTOMER Ciba Specialty Chemicals Holding Inc. (CH) 2006-12-06 EP disclosed
WO-2005059022-A1 COUPLING AGENTS BETWEEN FILLER AND ELASTOMER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-06-30 WO disclosed
WO-2004104051-A1 BIMOLECULAR PHOTOINITIATOR SYSTEMS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096115-A1 Oxime Ester Photoinitiators NR2E3, CBR3, AHR APEX1 634/4885MAPT 4688/4885NPSR1 80/4885
US-20070257234-A1 Stabilization of Organic Materials LPO, SOD1, GPX1 APEX1 148/4885MAPT 550/4885NPSR1 3090/4885
US-20080157025-A1 Long Wavelength Shifted Benzotriazole Uv-Absorbers And Their Use TPMT, SULT1A1, HPRT1 APEX1 1360/4885MAPT 85/4885NPSR1 2764/4885
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 APEX1 146/4885MAPT 128/4885NPSR1 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.