Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16143391 | 0.98 | SLC6A5 (0.55) | SLC6A5TPMTPLA2G4BCA12CA1 | |
| SCHEMBL12431955 | 0.95 | PLA2G2A (0.59) | SLC6A5TPMTPLA2G4BCA12CA1 | |
| SCHEMBL12431968 | 0.94 | PLA2G2A (0.62) | PLA2G4BPLA2G2ATSHR | |
| SCHEMBL11435088 | 0.94 | PLA2G2A (0.62) | PLA2G4BPLA2G2ATSHR | |
| SCHEMBL38650624 | 0.94 | PLA2G2A (0.62) | PLA2G4BPLA2G2ATSHR | |
| SCHEMBL8636608 | 0.92 | SMN1; SMN2 (0.60) | SLC6A5TPMTCA12CA1CA2 | |
| SCHEMBL17874346 | 0.91 | TPMT (0.61) | TPMTCA12CA1CA2CA3 | |
| SCHEMBL7995915 | 0.90 | PLA2G2A (0.56) | PLA2G4BPLA2G2ATSHR | |
| SCHEMBL18033251 | 0.90 | LMNA (0.49) | SLC6A5TPMTPLA2G4BCA12CA1 | |
| SCHEMBL19970624 | 0.87 | TPMT (0.56) | TPMTCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786986-B1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | VIVOZON INC (KR) | 2018-02-28 | — | — | EP | disclosed |
| EP-2786986-B1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | VIVOZON INC (KR) | 2018-02-28 | — | — | EP | disclosed |
| CN-103958477-B | Benzamide derivatives and uses thereof | (株)威沃尊 | 2017-03-29 | — | — | CN | disclosed |
| US-9359346-B2 | Benzamide derivative and use thereof | VIVOZON, INC. (KR) | 2016-06-07 | — | — | US | disclosed |
| US-9359346-B2 | Benzamide derivative and use thereof | VIVOZON, INC. (KR) | 2016-06-07 | — | — | US | disclosed |
| US-9359346-B2 | Benzamide derivative and use thereof | VIVOZON, INC. (KR) | 2016-06-07 | — | — | US | disclosed |
| US-20140336378-A1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | VIVOZON, INC. (KR) | 2014-11-13 | — | — | US | disclosed |
| US-20140336378-A1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | VIVOZON, INC. (KR) | 2014-11-13 | — | — | US | disclosed |
| US-20140336378-A1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | VIVOZON, INC. (KR) | 2014-11-13 | — | — | US | disclosed |
| EP-2786986-A2 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | Vivozon Inc. (KR) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013081400-A2 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | 주식회사 비보존 (KR) | 2013-06-06 | — | — | WO | disclosed |
| EP-1419138-B1 | N- (1-DIMETHYLAMINOCYCLOALKYL)METHYL BENZAMIDE DERIVATIVES | ORGANON NV (NL) | 2008-10-29 | — | — | EP | disclosed |
| US-7126027-B2 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | AKZO NOBEL N.V. (NL) | 2006-10-24 | — | — | US | disclosed |
| US-20040242685-A1 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | N.V. ORGANON (NL) | 2004-12-02 | — | — | US | disclosed |
| EP-1419138-A1 | N- (1-DIMETHYLAMINOCYCLOALKYL)METHYL]BENZAMIDE DERIVATIVES | Akzo Nobel (NL) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003010132-A1 | N-[(1-DIMETHYLAMINOCYCLOALKYL)METHYL]BENZAMIDE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336378-A1 | NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF | TRPV1, TRPA1, TRPV5 | SLC6A5 1714/4885TPMT 2755/4885PLA2G4B 1307/4885 |
| US-20040242685-A1 | N-[(1-dimethylaminocycloalkyl)methyl]benzamide derivatives | SLC1A2, SLC6A1, KCNT2 | SLC6A5 26/4885TPMT 282/4885PLA2G4B 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.