Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93387 | 1.00 | PTGS2 (0.45) | PTGS2NPSR1CYP2D6SRCLMNA | |
| SCHEMBL157605 | 1.00 | PTGS2 (0.45) | PTGS2NPSR1CYP2D6SRCLMNA | |
| SCHEMBL28995220 | 0.98 | PTGS2 (0.44) | PTGS2NPSR1CYP2D6SRCLMNA | |
| SCHEMBL27745764 | 0.90 | TRPM8 (0.45) | LMNAALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6216112 | 0.86 | RAB9A (0.44) | ALDH1A1SMN1; SMN2TP53NPC1MAPT | |
| SCHEMBL6216109 | 0.86 | RAB9A (0.44) | ALDH1A1SMN1; SMN2TP53NPC1MAPT | |
| SCHEMBL14463144 | 0.82 | NPSR1 (0.44) | PTGS2NPSR1CYP2D6SRCLMNA | |
| SCHEMBL27567147 | 0.82 | ALDH1A1 (0.41) | PTGS2NPSR1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3381199 | 0.81 | ALOX5 (0.44) | LMNAALDH1A1SMN1; SMN2KMT2AALOX5 | |
| SCHEMBL21382545 | 0.81 | KMT2A (0.44) | CYP2D6ALDH1A1NPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4582436-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BicycleTX Limited (GB) | 2025-07-09 | — | — | EP | claimed |
| US-20240000957-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 | BICYCLETX LIMITED (GB) | 2024-01-04 | — | — | US | claimed |
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | BICYCLETX LIMITED (GB) | 2023-07-11 | — | — | US | claimed |
| US-20220289794-A1 | SYNTHETIC ANTIMICROBIAL PEPTIDES | AJK BIOPHARMACEUTICAL LLC (US) | 2022-09-15 | — | — | US | claimed |
| EP-4021476-A1 | SYNTHETIC ANTIMICROBIAL PEPTIDES | AJK Biopharmaceutical, LLC (US) | 2022-07-06 | — | — | EP | claimed |
| EP-3208279-B1 | MINI-HEPCIDIN PEPTIDES AND METHODS OF USING THEREOF | UNIV CALIFORNIA (US) | 2021-04-21 | — | — | EP | claimed |
| WO-2021042039-A1 | SYNTHETIC ANTIMICROBIAL PEPTIDES | AJK PHARMACEUTICAL LLC (US) | 2021-03-04 | — | — | WO | claimed |
| EP-2748183-B1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIV LEIPZIG (DE) | 2018-12-26 | — | — | EP | claimed |
| US-9718861-B2 | Potent ligands of the ghrelin receptor | UNIVERSITAET LEIPZIG (DE) | 2017-08-01 | — | — | US | claimed |
| EP-2373679-B1 | MINI-HEPCIDIN PEPTIDES AND METHODS OF USING THEREOF | UNIV CALIFORNIA (US) | 2017-03-08 | — | — | EP | claimed |
| CN-106188224-A | A kind of multiple target-point anti-cancer medicine and preparation method and application | 广东工业大学 | 2016-12-07 | — | — | CN | claimed |
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITAET LEIPZIG (DE) | 2015-10-01 | — | — | US | claimed |
| EP-2748183-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | Universität Leipzig (DE) | 2014-07-02 | — | — | EP | claimed |
| US-8435941-B2 | Mini-hepcidin peptides and methods of using thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-07 | — | — | US | claimed |
| WO-2013026927-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITÄT LEIPZIG (DE) | 2013-02-28 | — | — | WO | claimed |
| EP-2562181-A1 | Potent ligands of the ghrelin receptor | Universität Leipzig (DE) | 2013-02-27 | — | — | EP | claimed |
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | claimed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, ERBB2 | PTGS2 2504/4885NPSR1 551/4885CYP2D6 3268/4885 |
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | GIPR, GPR119, GRPR | PTGS2 2281/4885NPSR1 64/4885CYP2D6 4578/4885 |
| US-20220289794-A1 | SYNTHETIC ANTIMICROBIAL PEPTIDES | VIP, HM13, NGLY1 | PTGS2 4551/4885NPSR1 1082/4885CYP2D6 4664/4885 |
| US-20240000957-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 | EPHA2, EPHB2, ERBB2 | PTGS2 2504/4885NPSR1 551/4885CYP2D6 3268/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | PTGS2 1345/4885NPSR1 2246/4885CYP2D6 4293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.